Development of ultra-sensitive nano-biosensor:

    Prof. Singh’s endeavour to develop next-generation ultrasensitive nano-biosensors for the detection of infectious agents (malaria, dengue) & disease biomarkers (cardiac infarction, cancer) has addressed the urgent necessity of developing inexpensive, highly accurate/sensitive, robust, easy-to-use, point of care diagnostic devices.
    To this end, Prof. Singh developed novel nanomaterials such as Cabron Nano Tube (CNT) doped ZnO electro spun Nanowire and engineered an innovative, one step, in-situ functionalization method. The chemiresistive /electrochemical device based on this approach is not only one of the most sensitive but also the first ever successful POC diagnostic platforms for the quantitative and qualitative analysis reported to date in the world. This work was published in various high impact scientific journals and received second best poster award in prestigious IEEE Sensors conference 2017 at Glasgow, UK Gandhian Young Technological Innovation (GYTI) Award and Medal from The President of India.
    The technology was demonstrated in Rashtrapati Bhavan, where it attracted accolades from erudite experts. It was further recognized through INAE Innovative Student Best Thesis Award 2018, BIRAC-SRISTI granted Rs.15 lakhs for product development because this technology has the potential for reaching the masses and addressing important social needs. Notably, Avanteal Diagnostics (USA) is commercializing this technology.

    Development of sensor for detecting adulteration in milk:

    Prof. Singh is an ardent believer in taking innovations beyond the confines of the academic domain to the realm of the greater public good. With this idea, he decided to tackle the menace of milk adulteration, the most alarming food safety concern in India.
    Currently, up to 37 different substances are being used as milk adulterants, rendering the existing adulterant specific methods time consuming, expensive and largely ineffective. Prof. Singh, therefore, devised an entirely unconventional approach to detect milk adulteration by monitoring the inherent biophysical properties (markers) of milk . He, for the first time, demonstrated that the alterations in the markers are correlated to the presence/absence of adulterants in the milk and developed a tamper-proof approach, which can differentiate between pure and adulterated milk with 99.7% accuracy.
    This transformative, inexpensive and easy to use device, called “Raj-Hans”, enables individual dairy buyer and producers to ascertain milk purity in less than 2 min. The work has been shortlisted for GYTI Award 2019. Given its significance, this invention has been reported by at least 40 media outlets (Print, Social and Digital) in various languages throughout the country.
    In regard to this, Prof Singh has received several technology-transfer requests from the largest dairy product companies in India including Amul, Doodhwala, R-Biofarma & Kalpa Innovative Solutions and the offers are currently being evaluated.