Computational Genomics & Transcriptomics Laboratory

Web Services

Prediction Server

ColoRecPred

CRC-focused study developed QSAR models using GDSC data to predict anticancer ounds. Models showed robustness across 12 CRC cell lines with high R2 values. Common chemical descriptors, like KRFP314 fingerprint, enhanced insights. Identified anti-CRC FDA-approved drugs and integrated findings into user-friendly prediction Web server "ColoRecPred

PUBLICATION SERVER

Database

AagingBase

AgingBase" database compiles 282 anti-aging peptides from diverse sources. It provides comprehensive physicochemical analyses and search tools for peptide research. Accessible without restrictions, it aids in identifying potential peptide candidates for geriatric medicine advancement.

PUBLICATION SERVER

Database

MyeloDB

MyeloDB, a multi-omics database, aids in multiple myeloma (MM) research. It offers gene expression profiles, CRISPR-Cas9 screens, drug sensitivity data, and biomarkers. Researchers can access datasets, conduct analyses, and identify novel MM drug targets like CBFB and MANF.

PUBLICATION SERVER

Database

AMLdb

AMLdb serves as a comprehensive resource for AML research. It offers data on transcriptional, epigenetic dynamics, mutations, and drug sensitivity. Novel gene targets like CBFB and ENO1 have been identified, advancing therapeutic interventions for AML.

PUBLICATION SERVER
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ML Model

MLP-COO

MLP-COO is a DLBCL classification model with high accuracy (99.67%) that is built using multilayer perceptron ,i.e., subtype of feedforward artificial neural network (ANN). This model classify DLBCL cases on the basis of gene expression into ABC (activating B-cell like) and GCB ( germinal center B-cell like)

PUBLICATION GITHUB

Tool

tumorVQ

tumorVQ is a package designed for the accurate quantification of brain tumor volumes from different brain regions using MRI scans. It provides user-friendly functions for volumetric analysis, integrating standard atlases and offering efficient data for radiogenomics research.

GITHUB

Web-platform

RadGLO

RadGLO is an interactive web-platform used for radiomics and radiogenomics analysis of glioma. This platform integrates imaging data, radiomics features, and clinical data for both low-grade glioma (LGG) and high-grade glioma (HGG).

PUBLICATION SERVER

Database

eVGeMdb

eVGeMdb is a manually curated database for experimentally validated genetic modifiers of Neurodegenerative Disorders. This platform catalogs over 17,000 genetic modifiers for key neurodegenerative disorders, including Amyotrophic Lateral Sclerosis, Alzheimer's, Parkinson's, Huntington’s, and Ataxia.

PUBLICATION SERVER

Database

OncoeQTM

OncoeQTM is an interactive platform for exploring Expression Quantitative Trait Methylation (eQTM) associations across 27 cancer types. eQTMs reveal how DNA methylation, an epigenetic modification, can regulate gene expression, providing critical insights into cancer mechanisms.

SERVER

Database

AGEX

AGEX - Alagille Genetics Exploration Database is a curated collection of mutations identified from literature and unpublished cases reported by clinicians. This database compiles mutations associated with the JAG1 and NOTCH2 genes in diverse populations.

SERVER

Database

PlasmoRhythm

PlasmoRhythm is a comprehensive database resource for malaria-associated rhythmic transcripts, proteins, and metabolites. It offers an interactive, web-based platform for comprehensively hosting, exploring, and analyzing rhythmic patterns in malaria parasites, their hosts, and mosquito vectors.

SERVER