TBT enables cloud based decentralized design and decentralized manufacturing. The issue is how do we realize this in a robust efficient and affordable manner

Processing and communication of bytes in TBT is a great enabler; but what is the kind of processing that will enable and enhance digital fabrication.

TBT is changing Just-in-Time-Delivery to Just-in-Time-Manufacturing. This offers a host of new challenges like quality certification, accessibility of the design only to authorized users, etc.

Design of specific shaped highly porous scaffold for tissue engineering application using biomaterials

How to take it to the next level of printing cells: Organ printing and extracellular matrix as per the organ.

Embedding security chips like RFIDs in digitally fabricated things

How enable IoT (Internet of Things) during Digital Fabrication - the challenge will be to create self-powered IoT.

Exploring new CAD standards to accommodate gradient structure and properties.

Exploring material aspects of the process like sintering and microstructure-properties correlation of metal powders (such as Titanium, Shape Memory alloys and Superalloys) and development of metal matrix Composites.

Exploring digital fabrication of microreactors for production of enzyme with high purity, printing of reaction vessels for drug synthesis and exploring different reactor designs.

Exploring 3D digital fabrication of intricate microfluidic device for 3-D tissue culture in hydrogel that can be used for regenerative medicine and drug screening.