About RMS Lab

In Regenerative Medicine and Stem cell (RMS) Lab, we work with mesenchymal stem cells and cancer derived stem cells; and try to understand their interaction and differentiation potential with respect to chemical forces from Biomaterials and mechanical forces from Bioreactors. We use 3D bio-printing to understand the mechanisms of regenrative potential and in vitro disease models for osteochondral tissues and angiogenic tissues. The ultimate aim of this lab to find the application of our research by using bioengineering strategies.

 Current research interests of our Lab:

3D bio-printing of tissues using patient-derived stem cells

Primary isolation of cells from patient samples
Stem cell research (Mesenchymal and cancer derived
3D bio-printing of osteochondral tissues
Right figure showing: 3D printable SiO2 nanoparticle ink for patient specific bone regeneration. For details, refer Uday et al, 2019, RSC advances 9 (41), 23832-23842

Bio-mimicking smart designed biomaterials

Bio-mimicked surface pattern for stem cell differentiation
Chemically modified bioinks for 3D bioprinting and drug release application
Applicaiton of hydrogels for specific stem cell pathway differentiation
Molecular biological analyses of osteogenesis and angiogenesis pathways

Cancer-on-chips to study anti-cancer drugs against cancer stem cells

Study of cancer-derived stem cells affecting malignant tissue behavior
Microfluidic chips simulating physiology of stem cell culture and drug testing
Testing of novel anti-cancer drugs in 3D cancer organoid model

Designing devices for novel applications in Diabetes, In vitro fertilization

Design and fabrication of a islet like device using material engineering
Characterization and application of novel natural biomaterials derived from sea, eggshell
IOT device for embryo monitoring for in vitro fertilization