Main objective of our research group (LBCS) is to investigate chemical and biological macromolecular systems using spectroscopic, microscopic and computational methods. We use fluorescence based steady state and time resolved spectroscopy and microscopy techniques to understand interactions between key biomolecules such as proteins, DNA and RNA.
Our research objectives include;
- Characterization of the excited-state photophysical properties of molecules.
- Fluorescence spectroscopy and structural dynamics of serum and milk proteins.
- Biophysical analysis of protein-DNA/RNA interactions.
- Exploring the luminescence behavior of nanomaterials such as CDs, QDs and GOs.
Publications
Jyoti Vishwakarma, Sudhanshu Sharma, Dineshbabu Takkella, Krishna Gavvala*
Unveiling Differential Interaction Pattern for Iminium and Alkanolamine Forms of Sanguinarine with β-Lactoglobulin Protein
Int. J. Biol. Macromol., 2024, 137721.
Sudhanshu Sharma, Dineshbabu Takkella, Abhinav Srivastava, Jacek Czub, Subrahmanyam Sappati*, Krishna Gavvala*
Unraveling Energy Transfer and Fluorescence Quenching Dynamics in Biomolecular Complexes: A Comprehensive Study of Imiquimod-Rifampicin Interaction
Phys. Chem. Chem. Phys., 2024, 26, 26291.
Dineshbabu Takkella, Sudhanshu Sharma, Satyanarayana Samireddi*, Krishna Gavvala*
Probing Photoinduced Electron Transfer Events in Phenylferrocene-Corrole Dyad
Phys. Chem. Chem. Phys., 2024, 26, 21688.
Dineshbabu Takkella, Lara Martinez-Fernandez, Krishna Gavvala*
Solvent Effect on the Excited State Photophysics of Imiquimod: a DFT/TD-DFT and Spectroscopic Study
J. Photochem. Photobiol. A., 2024, 457, 115928.
Sudhanshu Sharma, Dineshbabu Takkella, Krishna Gavvala*
Probing Ionic Liquid Based Micellar Structures Using the Photophysical Properties of a Plant Alkaloid: Spectroscopy and Microscopy Based Approach
J. Mol. Liq., 2024, 401, 124632.
Jyoti Vishwakarma, Dineshbabu Takkella, Sudhanshu Sharma, Krishna Gavvala*
Modulation of Excimer Formation and Photostability of Avobenzone inside the Nanocavities of Cyclodextrins
J. Photochem. Photobiol. A., 2024, 449, 115411.
Dineshbabu Takkella, Sudhanshu Sharma, Jyoti Vishwakarma, Javier Cerezo, Lara Martinez-Fernandez, Krishna Gavvala*
Unveiling the Interaction Modes of Imiquimod with DNA: Biophysical and Computational Studies
J. Photochem. Photobiol. A., 2024, 447, 115190.
Sudhanshu Sharma, Dineshbabu Takkella, Jyoti Vishwakarma, Krishna Gavvala*
Spectroscopy and Dynamics of beta-Lactoglobulin Complexed with Rifampicin
J. Biomol. Struct. Dyn., 2023, 1-14.
Dineshbabu Takkella, Sudhanshu Sharma, Radoslaw Krzemieniecki, Ashok Pabbathi, Subrahmanyam Sappati, Krishna Gavvala*
Targeting Spike-ACE2 Interface of SARS-CoV-2 and its Omicron Variant: A Comparative Screening of Potential Inhibitors for Existing and Anticipating Variants Using Molecular Modelling Approach
ChemistrySelect, 2023, 8 (32), e202302687.
Madushmita Hatimuria, Joydeep Das, Krishna Gavvala, Soumabha Bag, Ashok Pabbathi*
Recent Advances in the use of Laccase Enzyme in Deep Eutectic Solvents
Sustain. Chem. Pharm., 2023, 33, 101148.
Madushmita Hatimuria, Plabana Phukan, Soumabha Bag, Jyotirmoy Ghosh, Krishna Gavvala, Ashok Pabbathi*, Joydeep Das*
Green Carbon Dots: Applications in Development of Electrochemical Sensors, Assessment of Toxicity as Well as Anticancer Properties
Catalysts, 2023, 13 (3), 537.
Sudhanshu Sharma, Dineshbabu Takkella, Pintu Kumar, Krishna Gavvala*
Spectroscopic Analysis to Identify the Binding Site for Rifampicin on Bovine Serum Albumin
Spectrochim. Acta. A., 2022, 283, 121721.
Dineshbabu Takkella, Sudhanshu Sharma, Lara Martinez-Fernandez*, Krishna Gavvala*
Excited-State Dynamics of Imiquimod in Aqueous Solutions
J. Photochem. Photobiol. A., 2022, 431, 113998.
Stefano Ciaco, Krishna Gavvala, Vanille Greiner, Viola Mazzoleni, Pascal Didier, Marc Ruff, Lara Martinez-Fernandez, Roberto Improta, Yves Mély*
Thienoguanosine Brightness in DNA Duplexes is Governed by the localization of its ππ* Excitation in the Lowest Energy Absorption Band
Methods Appl. Fluoresc., 2022, 10, 035003.
Complete List of Publications
Jyoti Vishwakarma, Sudhanshu Sharma, Dineshbabu Takkella, Krishna Gavvala*
Unveiling Differential Interaction Pattern for Iminium and Alkanolamine Forms of Sanguinarine with β-Lactoglobulin Protein
Int. J. Biol. Macromol., 2024, 137721.
Sudhanshu Sharma, Dineshbabu Takkella, Abhinav Srivastava, Jacek Czub, Subrahmanyam Sappati*, Krishna Gavvala*
Unraveling Energy Transfer and Fluorescence Quenching Dynamics in Biomolecular Complexes: A Comprehensive Study of Imiquimod-Rifampicin Interaction
Phys. Chem. Chem. Phys., 2024, 26, 26291.
Dineshbabu Takkella, Sudhanshu Sharma, Satyanarayana Samireddi*, Krishna Gavvala*
Probing Photoinduced Electron Transfer Events in Phenylferrocene-Corrole Dyad
Phys. Chem. Chem. Phys., 2024, 26, 21688.
Dineshbabu Takkella, Lara Martinez-Fernandez, Krishna Gavvala*
Solvent Effect on the Excited State Photophysics of Imiquimod: a DFT/TD-DFT and Spectroscopic Study
J. Photochem. Photobiol. A., 2024, 457, 115928.
Sudhanshu Sharma, Dineshbabu Takkella, Krishna Gavvala*
Probing Ionic Liquid Based Micellar Structures Using the Photophysical Properties of a Plant Alkaloid: Spectroscopy and Microscopy Based Approach
J. Mol. Liq., 2024, 401, 124632.
Jyoti Vishwakarma, Dineshbabu Takkella, Sudhanshu Sharma, Krishna Gavvala*
Modulation of Excimer Formation and Photostability of Avobenzone inside the Nanocavities of Cyclodextrins
J. Photochem. Photobiol. A., 2024, 449, 115411.
Dineshbabu Takkella, Sudhanshu Sharma, Jyoti Vishwakarma, Javier Cerezo, Lara Martinez-Fernandez, Krishna Gavvala*
Unveiling the Interaction Modes of Imiquimod with DNA: Biophysical and Computational Studies
J. Photochem. Photobiol. A., 2024, 447, 115190.
Sudhanshu Sharma, Dineshbabu Takkella, Jyoti Vishwakarma, Krishna Gavvala*
Spectroscopy and Dynamics of beta-Lactoglobulin Complexed with Rifampicin
J. Biomol. Struct. Dyn., 2023, 1-14.
Dineshbabu Takkella, Sudhanshu Sharma, Radoslaw Krzemieniecki, Ashok Pabbathi, Subrahmanyam Sappati, Krishna Gavvala*
Targeting Spike-ACE2 Interface of SARS-CoV-2 and its Omicron Variant: A Comparative Screening of Potential Inhibitors for Existing and Anticipating Variants Using Molecular Modelling Approach
ChemistrySelect, 2023, 8 (32), e202302687.
Madushmita Hatimuria, Joydeep Das, Krishna Gavvala, Soumabha Bag, Ashok Pabbathi*
Recent Advances in the use of Laccase Enzyme in Deep Eutectic Solvents
Sustain. Chem. Pharm., 2023, 33, 101148.
Madushmita Hatimuria, Plabana Phukan, Soumabha Bag, Jyotirmoy Ghosh, Krishna Gavvala, Ashok Pabbathi*, Joydeep Das*
Green Carbon Dots: Applications in Development of Electrochemical Sensors, Assessment of Toxicity as Well as Anticancer Properties
Catalysts, 2023, 13 (3), 537.
Sudhanshu Sharma, Dineshbabu Takkella, Pintu Kumar, Krishna Gavvala*
Spectroscopic Analysis to Identify the Binding Site for Rifampicin on Bovine Serum Albumin
Spectrochim. Acta. A., 2022, 283, 121721.
Dineshbabu Takkella, Sudhanshu Sharma, Lara Martinez-Fernandez*, Krishna Gavvala*
Excited-State Dynamics of Imiquimod in Aqueous Solutions
J. Photochem. Photobiol. A., 2022, 431, 113998.
Stefano Ciaco, Krishna Gavvala, Vanille Greiner, Viola Mazzoleni, Pascal Didier, Marc Ruff, Lara Martinez-Fernandez, Roberto Improta, Yves Mély*
Thienoguanosine Brightness in DNA Duplexes is Governed by the localization of its ππ* Excitation in the Lowest Energy Absorption Band
Methods Appl. Fluoresc., 2022, 10, 035003.
Complete List of Publications